Laboratory of Biochemistry and Viruses
COMPOSITION OF THE LABORATORY
Head of the laboratory – Naila Galiveevna Klivleeva, Candidate of Biological Sciences
Laboratory staff:
Head of the laboratory – Naila Galiveevna Klivleeva, Candidate of Biological Sciences
Laboratory staff:
- Glebova Tatiana Ivanovna, Candidate of Biological Sciences, Leading Researcher;
- Shamenova Mira Galautdinovna, Candidate of Biological Sciences, Senior Researcher;
- Lukmanova Galina Vasilyevna, Master of Natural Sciences, Researcher;
- Saktaganov Nurbol Temirbaevich, Master of Veterinary Medicine, Researcher;
- Nurai Syrlybaevna Ongarbayeva, Master of Natural Sciences, Researcher;
- Bayseit Sagadat Bakhyt-kyzy, Master of Natural Sciences, Junior Researcher;
- Baymukhametova Asem Maratovna, Bachelor of Public Health, Junior Researcher;
- Kalkozhaeva Mereke Kozhakhmet-kyzy, Master of Technical Sciences, Junior Researcher;
- Daria Azamatovna Ismagulova, Bachelor of Biotechnology, laboratory assistant.
- Conducting continuous monitoring of acute respiratory viral infections and influenza circulating in the population of humans and mammalian animals in various regions of Kazakhstan
- Study of molecular genetic variability of ARVI and influenza pathogens
- Study of resistance of respiratory viruses to chemotherapy drugs
- Development of test systems for the diagnosis of human and animal influenza infection
- ГФ «Генетические детерминанты устойчивости казахстанских вирусов гриппа к химиопрепаратам»
- ГФ «Молекулярно-биологическая характеристика и антигенные свойства эпидемически значимых штаммов вирусов гриппа, циркулирующих в Республике Казахстан»
- ГФ «Молекулярно-генетическая изменчивость вирусов гриппа свиней в Казахстане»
- Международный центр по борьбе с гриппом (МНТЦ) №К-2231 «Молекулярная характеристика вирусов свиного гриппа, циркулирующих в различных регионах Казахстана, и сравнение с современными вирусами гриппа человека» (2018-2021 гг.)
- viral Genome Sequencing (NGS);
- PCR analysis of human and mammalian respiratory viruses;
- ELISA for the determination of virus antigens or antibodies to them;
- isolation and identification of human and animal influenza viruses on developing chicken embryos and cell culture.
- Klivleeva N., Ongarbayeva N., Saktaganov N., Glebova T., Lukmanova G., Shamenova M., Baymukhametova A. Circulation of influenza virus A/H1sw2009 among pig populations in the Republic of Kazakhstan (2019) // Biotechnology and biotechnological equipment.- Volume 35, 2021.- No. S1.- S43–S44. (Q3, IF. 1.86)
- Saktaganov N.T., Klivleeva N.G., Ongarbayeva N.S., Glebova T.I., Lukmanova G.V., Baymukhametova A.M. Study of antigenic relationships and biological properties of swine flu virus A/H1N1 strains isolated in Northern Kazakhstan in 2018. Agricultural Biology, 2020, vol. 55, No. 2, pp. 355-363. (Scopus – project 46 – 2020) doi: 10.15389/agrobiology.2020.2.355English, UDC: 636.4:619:578(574.2)
- Klivleeva N.G., Ongarbayeva N.S., Baymukhametova A.M., Saktaganov N.T., Lukmanova G.V., Glebova T.I., Sayatov M.K., Berezin V.E., Nusupbaeva G.E., Aikimbayev A.M. Detection of influenza virus and pathogens of acute respiratory viral infections in the population of Kazakhstan during the epidemic the 2018-2019 season. Russian Journal of Infections and Immunity. 2021;11(1):137-147. ( In Russian.) (Cite Core 0.370 (Web of Science), (Scopus) https://doi.org/10.15789/2220-7619-DOI-1348
- Saktaganov N.T., Klivleeva N.G., Glebova T.I., Kalkozhaeva M.K., Lukmanova G.V., Ongarbayeva N.S., Bayseit S.B., Baymukhametova A.M., Shamenova M.G. Characteristics of biological properties of isolates of swine influenza virus A/H1N1 isolated in Aktobe region in 2014 G. // Veterinary medicine.- Moscow.- No.2.- 2019.- pp.21-25. Doi:10.30896/0042-4846.2019.22.2.21-25.( Web Sciences)
- Klivleeva N., Ongarbayeva N., Saktaganov N., Glebova T., Lukmanova G., Shamenova M., Bayseit S., Baymukhametova A., Kalkozhaeva M. Monitoring of swine flu viruses circulating in Kazakhstan in 2018 // Journal of Clinical Virology.- Copenhagen.- Denmark.- 2019.- p.60.
- Klivleeva N.G., Ongarbayeva N.S., Saktaganov N.T., Glebova T.I., Lukmanova G.V., Shamenova M.G., Sayatov M.Kh ., Berezin V.E., Nusupbaeva G.E., Aikimbayev A.M., Webby R.J. Circulation of influenza viruses among humans and pigs on the territory of Kazakhstan during 2017-2018 // Bulletin of the National Academy of Sciences of the Republic of Kazakhstan.- Volume 2, number 378 (2019), pp. 6-13. ISSN 2518-1467 (Online), ISSN 1991-3494 (printed). DPI:10.32014/2019.2518-1467.35
- Lukmanova G.V., Klivleeva N.G., Glebova T.I., Sayatov M.H., Ongarbayeva N.S., Saktaganov N.T., Shamenova M.G., Kalkozhaeva M.K., Bayseit S.B., Baymukhametova A.M., Amirasheva L.K., Webby R. J. Sensitivity from 2015 Kazakhstan viruses influenza to chemotherapeutic drugs // Bulletin of the National Academy of Sciences of the Republic of Kazakhstan.- No. 4.- 2018.- pp. 18-22.
- Pat. 33922 Republic of Kazakhstan, Strain of influenza virus H1N1 A/pig/Kostanay/23/14, used for the preparation of diagnostic drugs / Klivleeva N.G., Glebova T.I., Shamenova M.G., Lukmanova G.V., Saktaganov N.T., Kalkozhaeva M.K., Bayseit S.B., Mustafin M.K., Mustafin B.M. zareg. 20.09.2019, State Register of Inventions of the Republic of Kazakhstan.
- Pat. 33923 Republic of Kazakhstan, Strain of influenza virus H1N1 A/Aktobe/02/15, used for the preparation of diagnostic drugs / Klivleeva N.G., Glebova T.I., Shamenova M.G., Lukmanova G.V., Saktaganov N.T.,Ongarbayeva N.S., Kalkozhaeva M.K., Bayseit S.B., Baymukhametova A.M., Mustafin M.K., Mustafin B.M. zareg. 09/20/2019, State Register of Inventions of the Republic of Kazakhstan.
- Pat. 34781 Strain of influenza virus H1N1 A/Pavlodar/20/18, used for the preparation of diagnostic drugs / Klivleeva N.G., Glebova T.I., Lukmanova G.V., Saktaganov N.T., Ongarbayeva N.S., Shamenova M.G., Baymukhametova A.M., Korotetsky I.S., Bekzatova G.K. zareg. 08.10.2019, State Register of Inventions Of the Republic of Kazakhstan.
- Pat. 34781 Strain of influenza virus H1N1 A/pig/Petropavlovsk/03/18, used for the preparation of diagnostic drugs / Klivleeva N.G., Ongarbayeva N.S., Saktaganov N.T., Glebova T.I., Lukmanova G.V., Kalkozhaeva M.K., Baymukhametova A.M., Korotetsky I.S., Mustafin M.K., Mustafin B.M. zareg. 08.10.2019, State Register of Inventions of the Republic of Kazakhstan.
- Pat. 34785 Strain of influenza virus H1N1 A/Almaty/04/18, used for the preparation of diagnostic drugs / Klivleeva N.G., Glebova T.I., Lukmanova G.V., Saktaganov N.T., Ongarbayeva N.S., Bayseit S.B., Baymukhametova A.M., Baymakhanova B.B., Shamenova M.G. zareg. 28.10.2019, State Register of Inventions of the Republic of Kazakhstan.
- Pat. 32011 Extract of Psoralea drupacea Bge., which has antiviral activity against the H5N3 avian influenza virus / Klivleeva N.G., Baisalova G.Zh., Pankrushina N.A., Glebova T.I., Lukmanova G.V. // Byul. 28.04.2017, No. 8.
- Pat. 32595 Strain of influenza virus H1N1 A/Almaty/856/12, used for the preparation of diagnostic drugs / Klivleeva N.G., Glebova T.I., Shamenova M.G., Baymakhanova B.B., Bayseit S.B. // Byul. 29.12.2017, No.26(II).
- Pat. 32594 Strain of influenza virus H1N1 A/pig/Kostanay/06/12, used for the preparation of diagnostic drugs / Klivleeva N.G., Shamenova M.G., Glebova T.I., Kuznetsova T.V. // Byul. 29.12.2017, No.26(II).
- Pat. 30125 Strain of influenza virus H1N1 A/Atyrau/874/12, used for the preparation of diagnostic drugs / Klivleeva N.G., Shamenova M.G., Glebova T.I., Baymakhanova B.B., Kuznetsova T.V. // Of. Byul. "Industrial property" 15.07.2015, No. 7.
