Laboratory of Molecular Virology
COMPOSITION OF THE LABORATORY
Head of the laboratory – Aleksyuk Pavel Gennadievich, Candidate of Biological Sciences, Scopus ID 57189593432
Laboratory staff:
Head of the laboratory – Aleksyuk Pavel Gennadievich, Candidate of Biological Sciences, Scopus ID 57189593432
Laboratory staff:
- Abugalieva Saule Tleuovna, Candidate of Biological Sciences, Leading Researcher
- Omirtaeva Elmira Serikkazinovna, Researcher;
- Manakbayeva Adalat, laboratory assistant.
- Molecular and phylogenetic analysis, genetic mapping of viruses;
- Study of viral infection blocking mechanisms and development of new antiviral drugs
- setting up PCR;
- conducting sequencing.
- Alexyuk M.S., Turmagambetova A.S., Alexyuk P.G., Bogoyavlenskiy A.P., Berezin V.E. Comparative study of viromes from freshwater samples of the Ile-Balkhash region of Kazakhstan captured through metagenomic analysis // Virus Disease. – 2017. - V. 28, No1. - P. 18-25. DOI: 10.1007/s13337-016-0353-5.
- Turmagambetova A.S., Alexyuk M.S., Bogoyavlenskiy A.P., Linster M., Alexyuk P.G., Zaitceva I.A., Smith G.J.D., Berezin V.E. Monitoring of Newcastle disease virus in environmental samples // Archives of Virology. - 2017. DOI: 10.1007/s00705-017-3433-y.
- Turmagambetova A.S., Alexyuk M.S., Alexyuk P.G., Bogoyavlenskiy A.P., Berezin V.E. Metagenomic analysis of NDV matrix protein gene from environmental samples // Acta Naturae. – 2017. – Special issue №1. – V. 9. – P. 43.
- Alexyuk M.S., Alexyuk P.G., Turmagambetova A.S., Bogoyavlenskiy A.P., Berezin V.E. Diversity of viral metabolic psb A gene in lake Balkhash // Acta Naturae. – 2017. – Special issue №1. – V. 9. – P. 42.
- Turmagambetova A.S., Alexyuk P.G., Bogoyavlenskiy A.P., Zaitseva I.A., Omirtaeva E.S., Alexyuk M.S., Sokolova N.S., Berezin V.E. Adjuvant activity of saponins from Kazakhstani plants on the immune responses to subunit influenza vaccine // Archives of Virology. - 2017. – Vol. 162, No 12. – P. 3817-3826. DOI: 10.1007/s00705-017-3560-5.
- Alexyuk P. G., Bogoyavlenskiy A. P., Alexyuk M. S., Turmagambetova A. S., Zaitseva I. A., Omirtaeva· E. S., Berezin V. E. Adjuvant activity of multimolecular complexes based on Glycyrrhiza glabra saponins, lipids, and influenza virus glycoproteins// Archives of Virology. -2019. - Vol. 164, No7.- P. 1793–1803, DOI: 10.1007/s00705-019-04273-2
- Moldakhanov YS, Alexyuk MS, Bogoyavlenskiy AP, Alexyuk PG, Turmagambetova AS, Zaitseva IA, Sokolova NS, Akanova KS, Anarkulova EI, Omirtaeva ES, Berezin VE. Complete genome sequence of Escherichia-infecting phage CEC_KAZ_2018, isolated from soil // Microbiol Resour Announc.- 2019. - 8:e00540-19. DOI: 10.1128/MRA .00540-19.
- Alexyuk M., Bogoyavlenskiy A., Alexyuk P., Moldakhanov Y., Turmagambetova A., Anarkulova E., Berezin V. Complete Genome Sequence of vB_EcoP_PR_Kaz2018, a T7-Like Bacteriophage // Microbiol Resour Announc. - 2019. - 8:e01323-19. DOI: 10.1128/MRA.01323-19
- Turmagambetova A.S., Alexyuk M.S., Bogoyavlenskiy A.P., Alexyuk P.G., Zaitseva I.A., Omirtaeva E.S., Sokolova N.S., Berezin V.E. Effect of the nanocapsulated adjuvant Sapomax on the expression of some immune response genes // Archives of Virology. -2020. – Vol. 165. – P. 1445–1451. https://doi.org/10.1007/s00705-020-04619-1
- Alexyuk M.S., Bogoyavlenskiy A.P., Alexyuk P.G., Moldakhanov Y.S., Berezin V.E. Metagenome Analysis of Surface Waters of the Shardara Reservoir, the Largest Artificial Reservoir in Southern Kazakhstan // Microbiol Resour Announc. – 2020. – Vol. 9, No 11. -:e00053-20. DOI: 10.1128/MRA.00053-20.
- Alexyuk M., Bogoyavlenskiy A., Alexyuk P., Moldakhanov Y., Berezin V., Digel I. Epipelagic microbiome of the Small Aral Sea: Metagenomic structure and ecological diversity // MicrobiologyOpen – 2020. — Vol. 10,N1. - e1142. DOI: 10.1002/mbo3.1142
- Alexyuk M., Bogoyavlenskiy A., Alexyuk P., Moldakhanov Y., Berezin V., Digel I. Epipelagic microbiome of the Small Aral Sea: Metagenomic structure and ecological diversity // MicrobiologyOpen – 2020. — Vol. 10,N1. - e1142. DOI: 10.1002/mbo3.1142
- Bogoyavlensky A.P., Turmagambetova A.S., Berezin V.E., Aleksyuk M.S., Aleksyuk P.G. A set of degenerate oligonucleotides-primers for metagenomic studies. Patent of the Republic of Kazakhstan for invention No. 33403 dated 17.01.2019.
- Bogoyavlensky A.P., Aleksyuk M.S., Aleksyuk P.G., Turmagambetova A.S., Berezin V.E. A set of primers for detecting viruses in aqueous samples by polymerase chain reaction. Patent of the Republic of Kazakhstan for invention No. 33410 dated 21.01.2019.
- Bogoyavlensky A.P., Turmagambetova A.S., Berezin V.E., Aleksyuk M.S., Aleksyuk P.G., Zaitseva I.A., Omirtaeva E.S. Phytocomposition for the prevention and therapy of influenza. Patent of the Republic of Kazakhstan for invention No. 33543 dated 19.03.2019.
- Berezin V.E., Bogoyavlensky A.P., Aleksyuk P.G., Zaitseva I.A., Sadanov A.K. A method for obtaining an immunostimulator based on a nanocomplex of lipids and saponins from the plant mylnyanka officinalis (Saponaria officinalis). Patent of the Republic of Kazakhstan for invention No. 33392 dated 16.01.2019.
- Aleksyuk P.G., Turmagambetova A.S., Bogoyavlensky A.P., Aleksyuk M.S., Berezin V.E. An immunostimulating agent based on purified biologically active compounds of plant origin. Patent of the Republic of Kazakhstan for invention No. 34249 dated 28.01.2020.
- Bogoyavlensky A.P., Turmagambetova A.S., Berezin V.E., Aleksyuk M.S., Aleksyuk P.G. Antiviral composite agent of plant origin. Patent of the Republic of Kazakhstan for invention No. 34248 dated 20.02.2020.
- Turmagambetova A.S., Bogoyavlensky A.P., Berezin V.E., Aleksyuk P.G., Aleksyuk M.S. The use of patuletin (3,5,7,3*,4*- pentaoxy-6-methoxyflavonol) as an antiviral agent against various strains of influenza virus. Patent of the Republic of Kazakhstan for invention No. 34328 dated 03/16/2020.
